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Various inhibitors and other biologically active compounds
Biochemicals
OTAVA has extensive experience in the synthesis of highly valuable products for biotech and pharmaceutical applications around the world.

Our company offers a number of INHIBITORS and other biologically active compounds modulating activity of distinct targets (see below). These compounds are available in milligram and gram quantities. Custom and bulk quotes are also available.

Please contact us for quotes.

If you do not see a compound you are looking for, we offer Custom Synthesis Services. Please contact us for quotes and details.


Download ALL in ONE file: OTAVA_Noteworthy_March08.pdf OTAVA_INHIBITORS_OCTOBER_08.pdf (684 KB)


[BIOLOGICAL ACTIVITY] [CAS RN]
[CAT. NO][DOWNLOAD]
Cyclin D1-CDK4 Inhibitor "546102-60-7" 7070707035cyclin_D1-CDK4_inhibitor.pdf
Inhibitor of cyclin-dependent kinase 4 "359886-84-3" OTV-CINK4inhibitor_of_cyclin_dependent_kinase_4.pdf
Synthetic inhibitor of DNA-dependent protein kinase (DNA-PK); inhibitior of mammalian target of rapamycin signalling "168425-64-7" 7070707024inhibitor_of_DNA_dependent_protein_kinase.pdf
Extremely potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase "153436-54-5" 7020540711inhibitor_of_epidermal_growth_factor_EGF_receptor_tyrosine_kinase.pdf
Inhibitior of interaction between the translation initiation factors eIF4E and eIF4G "315706-13-9" 7070707011inhibitor_of_interaction_between_the_translation_initiation_factors_eIF4E.pdf
Novel histone deacetylase (HDAC) inhibitor "926908-04-5" 7070707016novel_histone_deacetylase_HDAC_inhibitor.pdf
Potent inhibitor of IgE-mediated mast cell
responses to allergens in vitro and in vivo. Also inhibits cyclin-dependent kinase 2 (CDK2)
 		 "211555-08-7" 7015070102potent_inhibitor_of_IgE_mediated_mast_cell_responses.pdf
New CK2 inhibitor from OTAVA with IC50 = 0.3 μM "19231-60-8" 7015980251new_CK2_inhibitor_from_OTAVA_with_IC50_0_3uM.pdf
New CK2 inhibitor from OTAVA with IC50 = 0.8 μM"300675-28-9" 0107830107new_CK2_inhibitor_from_OTAVA_with_IC50_0_8uM.pdf
New CK2 inhibitor from OTAVA with IC50 = 1.0 μM"51726-83-1" 0107830116new_CK2_inhibitor_from_OTAVA_with_IC50_1uM.pdf
Potent and selective inhibitor of IKK-epsilon kinase"862812-98-4"7020402324(2)selective_inhibitor_of_IKK_kinase.pdf
Antitumor agent activating procaspase-3
to caspase-3		"315183-21-2"7210801533antitumor_agent_activating_procaspase-3_to_caspase-3.pdf
Benzenesulfonanilide-type cyclooxygenase-1
selective inhibitor		"304913-22-2"7070707001benzenesulfonanilide-type_cyclooxygenase-1-selective_inhibitor.pdf
Bifeprunox  - a novel atypical antipsychotic
agent (custom quotes are available) 		"350992-10-8"7070707030
bifeprunox_antipsychotic_agent.pdf
CDK2-cyclin E inhibitor"140651-18-9"7020402317CDK2-cyclin_E_inhibitor.pdf
CFTR chloride channel inhibitor "307510-92-5"0129690030
CFTR_blocker.pdf
Glycogen synthase kinase-3 (GSK-3) inhibitor"601514-19-6"7070707013glycogen_synthase_kinase-3_(GSK-3)_inhibitor.pdf
Hypoxia-Inducible Factor-1 inhibitor"934593-90-5"7070707015Hypoxia-Inducible_factor-1_inhibitor.pdf
Inhibitor of eukaryotic elongation factor 2 kinase "278603-08-0"7070707012inhibitor_ of_eukaryotic_elongation_factor_2.pdf
Potent inhibitor of sirtuin 2 (SIRT2)"304896-28-4"0117392020inhibitor_of_sirtuin_2_(SIRT2).pdf
Inhibitor of STAT3 with anti-tumor activity"501919-59-1"7070707021inhibitor_of_STAT3.pdf
Janus kinase 3 (JNK3) inhibitor"202475-60-3"7015070103Janus_kinase_3_(JNK3)_inhibitor.pdf
Potent and selective inhibitor of IKK-epsilon kinase"916985-21-2"7020402323selective_inhibitor_of_IKK_kinase.pdf
Selective inhibitor of the deacetylase SIRT1"49843-98-3"7020402314selective_inhibitor_of_the_deacetylase_SIRT1.pdf
Cambinol - SIRT1/2 Inhibitor IV"14513-15-6"7020402315SIRT1-2_Inhibitor_IV_Cambinol.pdf





Prescreened libraries for cancer research
Biochemicals
We propose sets of anticancer compounds evaluated in vitro on 60 human tumor cell lines. The sets contain compounds that have GI50 in submicromolar range.

[CANCER TYPE]

[GI 50]

Leukemia

Set of 95 compounds with GI 50 from < 10 -8 M to 10 -6 M

Non-Small Cell Lung Cancer

Set of 90 compounds with GI 50 from < 10 -8 M to 10 -6 M

Colon Cancer

Set of 68 compounds with GI 50 from < 10 -8 M to 10 -6 M

CNS Cancer

Set of 73 compounds with GI 50 from < 10 -8 M to 10 -6 M

Melanoma

Set of 85 compounds with GI 50 from < 10 -8 M to 10 -6 M

Ovarian Cancer

Set of 71 compounds with GI 50 from < 10 -8 M to 10 -6 M

Renal Cancer

Set of 90 compounds with GI 50 from < 10 -8 M to 10 -6 M

Prostate Cancer

Set of 58 compounds with GI 50 from < 10 -7 M to 10 -6 M

Breast Cancer

Set of 84 compounds with GI 50 from < 10 -8 M to 10 -6 M

The sets of anticancer compounds are available on request. Feel free to contact us
Brand-new compounds | Fragment library | Compound libraries for HTS | Focused libraries | Biochemicals | Building blocks | Fluoresent dyes