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Ion Channel Targeted Libraries

Ion channel focused libraries

To date, ion channel modulators have been identified by various means, relatively few of which have so far been focused on direct screening of compounds for their activity on the channel(s) of interest. The past few years have seen significant developments that facilitate the identification of novel ion channel modulators. These improvements in screening methods should lead to more selective agents being identified and progressing into clinical development.

 

 

 

 
For the moment, Otava offers 3 Ion Channel Targeted Libraries designed with Ligand-based approach. These libraries are proposed for screening in ion channel-associated research and drug development projects.

  • the libraries contain drug-like compounds only
  • all the compounds are in stock
  • cherry picking is available

 

 

Name Number of compounds Approach
Calcium Channel Antagonist 165 Ligand-based
Sodium Channel Blocker 1473 Ligand-based
Sodium channel blocker class Ib - Ligand-based

Otava's Target-Focused Libraries collection
Name Number
Kinases 67
Proteases 12
GPCRs 24
Ion channels 3
Disease-based libraries 29
Epigenetic targets 6
Protein-Protein Interaction 2
Peptidomimetic 1
Nuclear Receptors 1
General Activities 127
Other 101

 

 

The libraries (SDF, XLS, PDF format) are available on request. Feel free to contact us or use on-line form below to send an inquiry if you are interested to obtain these libraries or if you need more information.

 

 

 

 

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