
Phenotypic drug discovery is successful strategy that allows to identify substances (small molecules, peptides etc.) which alter the phenotype of cells, tissues or whole organisms in a desired manner.
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Natural Product-Like Library has been designed as a special screening library containing synthetic compounds similar to natural.
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CNS Compound Library from OTAVAchemicals has been designed as a special screening library containing compounds with high blood brain barrier (BBB) permeability.
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OTAVAchemicals offers synthesis of chemical libraries on the basis of rare scaffolds. Our scaffold database was prepared using comparative analysis of worldwide suppliers of chemical compounds. This is your opportunity to get novel compounds for screening purposes!
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OTAVAchemicals screening collection contains about 260,000 compounds for prompt delivery. All compounds have undergone quality control to confirm their chemical structures. We offer the possibility to re-supply compounds purchased from us.
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OTAVAchemicals offers a collection of Tangible Screening Compounds and it includes about 6,050,000 compounds where "tangible" denotes structures with a high likelihood of being synthesized. Typically these are chemical schemes that have been validated although not yet put into production or where only a very small proportion of the possible final compounds have been synthesized. The compounds ordered from this collection could be individually synthesized and delivered within 4 weeks.
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Our drug-like Green Collection compound library (about 176,000 compounds in total) was prepared on the basis of Screening Compounds for Prompt Delivery and pre-formatted by Lipinski's Rules of Five:
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Optimization of lead compounds into drugs adds substructures onto the lead template to enhance target affinity and selectivity.
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OTAVAchemicals Diversity Libraries PrimScreen1, PrimScreen2, PrimScreen3, PrimScreen5, PrimScreen10 and PrimScreen15 are prepared by diversity sorting
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