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Contract Research

Contract ResearchOTAVAchemicals is a science-based contract research organization that provides a full range of services relating to early drug discovery. The quality and reliability we offer is established from the company’s long-standing experience of over 15 years in the industry. We have developed a reputation as a trustworthy and experienced outsourcing partner and have a strong background in organic and medicinal chemistry, biochemistry and molecular modeling. Please see the list of our publications. We would be glad to respond to any project proposal, and are ready to sign a non-disclosure agreement prior to any discussions. 

 

 

The services we provide include the following:

  • Custom Synthesis (Read more...)
  • Molecular modeling and virtual screening, hit-to lead optimization Read more...)
  • Bioinformatics (Read more...)
  • Chemistry Consulting
    • We provide comprehensive chemistry consulting in the field of medicinal chemistry research, chemical libraries and organic synthesis at a reasonable cost.

 

 

 

WHY TO CHOOSE OUR CUSTOM SYNTHESIS SERVICE?

  • Creativity and problem solving in the field of chemistry/biology
  • Weekly progress reports
  • Competitive pricing and fast turn-around time
  • Reliability and strict confidentiality
  • Prompt response policy
  • FTE (Full Time Equivalent) & FFS (Fee For Services) projects

 

Our company has extensive experience in the area of custom synthesis/contract research and guarantees quality results, competitive pricing, and a fast turn-around time. 
 
We already collaborate with many companies and academic institutions in Europe, the U.S. and Canada; we hope you will consider working with us for your next project.
 
 

Our products are a part of Sigma-Aldrich product catalog

 
PEOPLE AND FACILITIES
 
Our research facilities are located in North America, namely in Toronto, Kingston and Vaughan (Ontario, Canada) and Europe (Kyiv, Ukraine). We have fully equipped chemical laboratories with a well-developed infrastructure and routine access to NMR and LC-MS facilities. Full data (1H and 13C NMR, LRMS, HRMS and HPLC) is provided for all compounds to support their purity. Elemental analysis can be provided upon request. 

 

 

What we can do in our laboratories

  • Synthetic chemistry
  • Bioorganic chemistry
  • Medicinal chemistry
  • High-throughput (Hit-to-Lead & Lead Optimization) chemistry
  • Computational Chemistry / Cheminformatics
  • General Consulting

 

 

 

Instrumentation

  • Three quadrupole tandem mass spectrometers for LC/MS analysis in APCI or ESI MS or MS/MS
  • 300 MHz Multinuclear NMR
  • Semi-preparative HPLC systems
  • Two analytical HPLC systems with photodiode array detectors
  • Two Biotage Isolera Flash Purification Systems
  • UV-Vis Spectrometer
  • GC/MS EI

 

If you decide to work with us, you would have acces to the services of qualified chemists with an extensive expertise in laboratory organic synthesis, catalysis, chemical product research and synthesis of heterocyclic compounds. The materials needed for research can be supplied in quantities ranging from milligrams to kilograms. Our team of highly skilled medicinal and computational chemists is ready to facilitate hit identification, target validation or hit-to-lead optimization  projects of any level. The team can work with many drug targets including, but not limited to, protein kinases, nuclear receptors, GPCRs and ion channels.

 

 

SPECIFICATIONS
  • Quality control by NMR and/or GC/LC/MS
  • Purity: 95%+
  • Custom support: structural modification, etc.
  • NMR and LC/MS/MS spectra are available upon request
  • Respond to inquiries within 24 hours
  • Weekly progress reports
  • Confidentiality and intellectual property (IP) protection guarantee
  • FTE (Full Time Equivalent) & FFS (Fee For Services) projects
  • Molecular modeling and computational chemistry procedures with modern state-of-the-art software and algorithms

 

 

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