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All Targeted Libraries

Full list of Focused LibrariesFull collection of more than  350 OTAVAchemicals Targeted Libraries designed with Receptor-based or Ligand-based approach is represented here.

These libraries are proposed for screening in various research and drug development projects.

 

 

 

  • the libraries contain drug-like compounds only
  • all the compounds are in stock
  • cherry picking is available

 

You can sort data by any column and use "Filter" option to search library's name:

Name Number of compounds Approach Details
1-Phosphatidylinositol-4-phosphate 5-kinase (PIPK) inhibitor library 14 Ligand-based -
Abl kinase inhibitor library 76 Ligand-based -
Acetate kinase inhibitor library 129 Ligand-based -
ADP-thymidine kinase inhibitor library 922 Ligand-based -
Aurora A kinase inhibitor library 364 Ligand-based -
Aurora B kinase inhibitor library 249 Ligand-based -
Aurora C kinase inhibitor library 1162 Ligand-based -
Beta-adrenergic receptor kinase (BARK) inhibitor library 1268 Ligand-based -
Check point kinase (CHK) inhibitor library 593 Ligand-based -
Cyclin-dependent kinase 1 (CDK1) inhibitor library 83 Ligand-based -
Cyclin-dependent kinase 2 (CDK2) inhibitor library 466 Ligand-based -
Cyclin-dependent kinase 4 (CDK4) inhibitor library 798 Ligand-based -
Cyclin-dependent kinase 5 (CDK5) inhibitor library 893 Ligand-based -
EphB2 kinase inhibitor library 329 Ligand-based -
Epidermal growth factor receptor (EGFR) kinase inhibitor library 318 Ligand-based -
Glycogen synthase kinase-3 (GSK3) inhibitor library 206 Ligand-based -
Glycogen synthase kinase-3 beta (GSK3B) inhibitor library 603 Ligand-based -
G-protein-coupled receptor kinase (GRK) inhibitor library 1268 Ligand-based -
Guanidinoacetate kinase inhibitor library 254 Ligand-based -
I kappa B kinase 2 (IKK2) inhibitor library 347 Ligand-based -
Inositol-trisphosphate 3-kinase (IP3K) inhibitor library 78 Ligand-based -
Lombricine kinase inhibitor library 163 Ligand-based -
Mitogen activated parotein kinase 1 (MAPK1) inhibitor library - Ligand-based -
MAP kinase (MAPK) inhibitor library 102 Ligand-based -
N-acylmannosamine kinase inhibitor library 935 Ligand-based -
NADH kinase inhibitor library 871 Ligand-based -
Opheline kinase inhibitor library 875 Ligand-based -
Phosphatidylinositol 3-kinase C2 beta (PI3K-C2 beta) inhibitor library 1183 Ligand-based -
Phosphatidylinositol 3-kinase C2 gamma (PI3K-C2 gamma) inhibitor library 252 Ligand-based -
Phosphoenolpyruvate carboxykinase (PEPCK) inhibitor library 26 Ligand-based -
Platelet derived growth factor receptor (PDGFR) kinase inhibitor library 1972 Ligand-based -
Protein kinase CK1 inhibitor library 1387 Ligand-based -
Protein kinase B (PKB) inhibitor library 1070 Ligand-based -
Protein kinase C eta (PKC) inhibitor library 16 Ligand-based -
Serine-threonine kinase inhibitor library 213 Ligand-based -
Proto-oncogene tyrosine protein kinase Fyn inhibitor library 481 Ligand-based -
Proto-oncogene tyrosine protein kinase Kit inhibitor library 214 Ligand-based -
Pyridoxal kinase inhibitor library 5 Ligand-based -
Raf kinase B inhibitor library 38 Ligand-based -
Raf kinase inhibitor library 74 Ligand-based -
Rho-associated kinase inhibitor library 344 Ligand-based -
Ribosomal protein S6 kinase (S6K) inhibitor library 10 Ligand-based -
Shikimate kinase inhibitor library 453 Ligand-based -
Smooth muscle myosin light chain kinase (MLCK) inhibitor library 627 Ligand-based -
Sphinganine kinase inhibitor library 244 Ligand-based -
Sphingosine kinase inhibitor library 1119 Ligand-based -
Src kinase inhibitor library 200 Ligand-based -
Taurocyamine kinase inhibitor library 875 Ligand-based -
Thymidine kinase inhibitor library 922 Ligand-based -
Tyrosine kinase inhibitor library 1147 Ligand-based -
Urokinase inhibitor library 21 Ligand-based -
P21-activated kinase 1 (PAK1) inhibitor library 606 Receptor-based read more
Serine/threonine kinase CHK1 inhibitor library 681 Receptor-based read more
Proto-oncogene tyrosine kinase ABL1 inhibitor library 771 Receptor-based read more
Extracellular signal-regulated kinase 2 (ERK2) inhibitor library 197 Receptor-based read more
Death-associated kinase 2 (DAPK2) inhibitor library 591 Receptor-based read more
p38 MAP kinase alpha inhibitor library 2221 Receptor-based read more
Vascular endothelial growth factor receptor 2 (VEGFR2) kinase inhibitor library 648 Receptor-based read more
Aurora B kinase inhibitor library 508 Receptor-based read more
Janus kinase 2 (Jak2) inhibitor library 625 Receptor-based read more
Phosphatidylinositol 3-kinase (PI3K) inhibitor library 364 Receptor-based read more
3-phosphoinositide-dependent kinase-1 (PDK-1) inhibitor library 496 Receptor-based read more
Cyclin-dependent kinase 2 (CDK2) inhibitor library 670 Receptor-based read more
Glycogen synthase kinase 3 (GSK3) inhibitor library 980 Receptor-based read more
Fibroblast growth factor receptor 1 kinase (FGFR1K) inhibitor library 485 Receptor-based read more
cAMP dependent protein kinase (PKA) inhibitor library 408 Receptor-based read more
C-Jun N-terminal kinase 2 (Jn2) inhibitor library 1774 Receptor-based -
Death-associated protein kinase 1 (DAPK1) inhibitor library 1962 Receptor-based -
Death-associated protein kinase 3 (DAPK3) inhibitor library 1814 Receptor-based -
DOT1-like histone H3 methyltransferase (DOT1L) inhibitor library 622 Receptor-based read more
Bromodomain-containing protein 4 (BRD4) inhibitor library 401 Receptor-based read more
Histone deacetylase (HDAC) inhibitor library 803 Receptor-based read more
DNA (cytosine-5)-methyltransferase 1 (DNMT1) inhibitor library 466 Receptor-based read more
DNA (cytosine-5)-methyltransferase 3 beta (DNMT3b) inhibitor library 1261 Receptor-based read more
Histone acetyltransferase (HAT) inhibitor library 814 Receptor-based read more
CREB binding protein (CREBBP) targeted library 576 Receptor-based read more
Protein Arginine Methyltransferases (PRMTs) Targeted Library 842 Receptor-based read more
Angiogenesis inhibitor library 1625 Ligand-based -
Antipsychotic 1315 Ligand-based -
Antiobesity 1714 Ligand-based -
Antimigraine 426 Ligand-based -
Antidepressant 1554 Ligand-based -
Anticonvulsant 1830 Ligand-based -
Anticarcinogenic 822 Ligand-based -
Antifungal 828 Ligand-based -
Antimycobacterial 1696 Ligand-based -
Antituberculosic 1828 Ligand-based -
Acaricide - Ligand-based -
Adrenergic - Ligand-based -
Adrenergic (ophthalmic) - Ligand-based -
Analeptic - Ligand-based -
Analgesic - Ligand-based -
Analgesic (non-opioid) - Ligand-based -
Anesthetic - Ligand-based -
Anesthetic general - Ligand-based -
Anesthetic inhalation - Ligand-based -
Anesthetic local - Ligand-based -
Anorexic - Ligand-based -
Antiadrenergic - Ligand-based -
Antiallergic - Ligand-based -
Antiamebic - Ligand-based -
Antianginal - Ligand-based -
Antiarrhythmic - Ligand-based -
Antibacterial - Ligand-based -
Anticataract - Ligand-based -
Anticoagulant - Ligand-based -
Antidiabetic - Ligand-based -
Antidiabetic symptomatic - Ligand-based -
Antiglaucomic - Ligand-based -
Antihelmintic - Ligand-based -
Antihistaminic - Ligand-based -
Antihypercholesterolemic - Ligand-based -
Antihypertensive - Ligand-based -
Antiinfective - Ligand-based -
Antiinflammatory - Ligand-based -
Antiinflammatory (intestinal) - Ligand-based -
Antiischemic (cerebral) - Ligand-based -
Antineoplastic - Ligand-based -
Antineoplastic enhancer - Ligand-based -
Antiosteoporotic - Ligand-based -
Antioxidant - Ligand-based -
Antiparasitic - Ligand-based -
Antiparkinsonian - Ligand-based -
Antiprotozoal - Ligand-based -
Antiprotozoal (Coccidial) - Ligand-based -
Antipsoriatic - Ligand-based -
Antipyretic - Ligand-based -
Antischistosomal - Ligand-based -
Antisecretoric - Ligand-based -
Antiseptic - Ligand-based -
Antithrombotic - Ligand-based -
Antitreponemal - Ligand-based -
Antitrypanosomal - Ligand-based -
Antitussive - Ligand-based -
Antiulcerative - Ligand-based -
Antiuremic - Ligand-based -
Antiviral - Ligand-based -
Anxiolytic - Ligand-based -
Bone diseases treatment - Ligand-based -
Bone formation stimulant - Ligand-based -
Bronchodilator - Ligand-based -
Capillary fragility treatment - Ligand-based -
Carcinogenic - Ligand-based -
Cardiodepressant - Ligand-based -
Cardiotonic - Ligand-based -
Choleretic - Ligand-based -
Cholesterol synthesis inhibitor library - Ligand-based -
Cholinergic - Ligand-based -
Cholinergic antagonist - Ligand-based -
CNS active muscle relaxant - Ligand-based -
Coagulant - Ligand-based -
Cognition disorders treatment - Ligand-based -
Cytostatic - Ligand-based -
Dermatologic - Ligand-based -
Diuretic - Ligand-based -
Diuretic inhibitor library - Ligand-based -
DNA synthesis inhibitor library - Ligand-based -
Embryotoxic - Ligand-based -
Expectorant - Ligand-based -
Free radical scavenger - Ligand-based -
Growth stimulant - Ligand-based -
Hemostatic - Ligand-based -
Hepatic disorders treatment - Ligand-based -
Hepatoprotectant - Ligand-based -
Hypertensive - Ligand-based -
Hypoglycemic - Ligand-based -
Hypolipemic - Ligand-based -
Hypotermic - Ligand-based -
Insecticide - Ligand-based -
Insulin secretagoues - Ligand-based -
Keratolytic - Ligand-based -
Miotic - Ligand-based -
Muscle relaxant - Ligand-based -
Mutagenic - Ligand-based -
Oxytocic - Ligand-based -
Protein synthesis inhibitor library - Ligand-based -
Psychotropic - Ligand-based -
Radioprotector - Ligand-based -
Radiosensitizer - Ligand-based -
Reductant - Ligand-based -
Renal disease treatment - Ligand-based -
Respiratory analeptic - Ligand-based -
Restenosis treatment - Ligand-based -
Saluretic - Ligand-based -
Sedative - Ligand-based -
Skeletal muscle relaxant - Ligand-based -
Skin irritative effect - Ligand-based -
Sleep disorders treatment - Ligand-based -
Spasmogenic - Ligand-based -
Spasmolytic - Ligand-based -
Spasmolytic (Papaverin-like) - Ligand-based -
Spasmolytic (urinary) - Ligand-based -
Sweetener - Ligand-based -
Teratogen - Ligand-based -
Ulcerogenic - Ligand-based -
Uric acid diuretic - Ligand-based -
Uricosuric - Ligand-based -
Urinary incontinence treatment - Ligand-based -
Uterine relaxant - Ligand-based -
Vasodilator - Ligand-based -
Vasodilator (coronary) - Ligand-based -
Antiviral (hepatitis C) - Ligand-based -
Antiviral (hepatitis) - Ligand-based -
Antiviral (poxvirus) - Ligand-based -
Antiviral (trachoma) - Ligand-based -
GPCR agonist general library 465 Ligand-based -
GPCR antagonist general library 5089 Ligand-based -
5-hydroxytryptamine agonist general library 199 Ligand-based -
5-hydroxytryptamine 1A agonist library - Ligand-based -
5-hydroxytryptamine 2 agonist library - Ligand-based -
5-hydroxytryptamine 3 agonist library - Ligand-based -
5-hydroxytryptamine antagonist general library 290 Ligand-based -
5-hydroxytryptamine 1A antagonist library 600 Ligand-based -
5-hydroxytryptamine receptor 1B antagonist library 1836 Receptor-based read more
5-hydroxytryptamine 2C antagonist library - Ligand-based -
5-hydroxytryptamine 2D antagonist library - Ligand-based -
5-hydroxytryptamine 6 antagonist library 42 Ligand-based -
Acetylcholine muscarinic agonist library 10 Ligand-based -
Alpha adrenoreceptor agonist library 45 Ligand-based -
Cholecystokinin agonist library 12 Ligand-based -
Dopamine agonist library 29 Ligand-based -
Dopamine autoreceptor agonist library 181 Ligand-based -
GABA receptor agonist library 117 Ligand-based -
Melatonin agonist library 17 Ligand-based -
Acetylcholine muscarinic antagonist library 81 Ligand-based -
Acetylcholine M2 receptor antagonist library - Ligand-based -
Acetylcholine M3 receptor antagonist library - Ligand-based -
Adenosine receptor antagonist library 110 Ligand-based -
Alpha adrenoreceptor antagonist library 1045 Ligand-based -
Alpha 1 adrenoreceptor antagonist library - Ligand-based -
Alpha 1a adrenoreceptor antagonist library - Ligand-based -
Alpha adrenoreceptor agonist general library - Ligand-based -
Alpha 1 adrenoreceptor agonist library - Ligand-based -
Alpha 2 adrenoreceptor agonist library - Ligand-based -
Beta adrenoreceptor antagonist library 89 Ligand-based -
Dopamine antagonist general library 61 Ligand-based -
Dopamine D3 antagonist library - Ligand-based -
Dopamine D4 antagonist library - Ligand-based -
Dopamine D3 agonist library - Ligand-based -
Endothelin receptor antagonist general library 165 Ligand-based -
Endothelin A receptor antagonist library - Ligand-based -
Endothelin B receptor antagonist library - Ligand-based -
GABA receptor antagonist library 1133 Ligand-based -
Glucagon receptor antagonist library 526 Ligand-based -
Glutamate receptor antagonist library 27 Ligand-based -
Histamine receptor antagonist library 590 Ligand-based -
Neuropeptide antagonist library 106 Ligand-based -
Prostaglandin antagonist library 665 Ligand-based -
Thromboxane antagonist library 133 Ligand-based -
Vasopressin 1 antagonist library 23 Ligand-based -
Histamine receptor targeted library 1295 Receptor-based read more
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker library 672 Ligand-based read more
Calcium channel blocker library 1262 Ligand-based read more
Sodium channel blocker library 1281 Ligand-based -
Voltage-gated sodium channel blocker library 1630 Ligand-based read more
Kv1.5 potassium channel blocker library 1052 Ligand-based read more
Glucocorticoid receptor antagonist library 1014 Receptor-based read more
Liver X receptor beta modulator library 560 Receptor-based read more
Estrogen Related Receptor Gamma (ERRγ) Targeted Library 950 Ligand-basedReceptor-based read more
Human presequence protease agonist library 1050 Ligand-based read more
Trypsin inhibitor library 51 Ligand-based -
Factor Xa inhibitor library 122 Ligand-based -
Tryptase inhibitor library 139 Ligand-based -
Cathepsin B inhibitor library 275 Ligand-based -
Cathepsin L inhibitor library 71 Ligand-based -
Cathepsin T inhibitor library 1550 Ligand-based -
Subtilisin inhibitor library 91 Ligand-based -
HCV serine protease inhibitor library 1300 Ligand-based -
Matrix metalloproteinase 1 inhibitor library 39 Ligand-based -
Matrix metalloproteinase inhibitor library 16 Ligand-based -
Metalloproteinase inhibitor library 21 Ligand-based -
Metalloproteinase-9 inhibitor library 608 Ligand-based -
Caseinolytic protease ClpP Targeted Library 825 Receptor-based read more
Caspase 2 Targeted Library 480 Receptor-based read more
SH2 Domain Targeted Library 1970 Ligand-based read more
Phenotypic screening library 5000 Ligand-based read more
Alzheimer's Disease Targeted Polypharmacology Library 631 Ligand-basedReceptor-based read more
Natural product-like library 1240 Ligand-based read more
Beta-turn peptidomimetic library 510 Ligand-based read more
a-Helix peptidomimetic library 590 Ligand-based read more
Sodium glucose cotransporter 2 (SGLT2) targeted library 687 Ligand-based read more
Glycomimetic Focused Library 233 Ligand-based read more
HMG-CoA reductase inhibitor library 806 Ligand-basedReceptor-based read more
11β-HSD1 targeted library 1060 Receptor-based read more
Protein-protein interactions (PPI) inhibitor library iPPI Tree 1330 Ligand-based read more
Protein-protein interactions (PPI) inhibitor library iPPI Bayesian 2310 Ligand-based read more
Poly (ADP-ribose) Polymerase 1 (PARP-1) targeted library 513 Ligand-basedReceptor-based read more
Dipeptidyl peptidase-4 (DPP4) targeted library 740 Ligand-basedReceptor-based read more
RNA targeted library 2894 Ligand-based read more
Hsp90 targeted library 634 Ligand-basedReceptor-based read more
Acetylcholinesterase (AChE) targeted library 828 Receptor-based -
Beta Secretase 1 (BACE1) inhibitor library 342 Ligand-based -
GABA A receptor agonist library - Ligand-based -
2 3-oxidosqualene lanosterol cyclase inhibitor library - Ligand-based -
5-hydroxytryptamine uptake inhibitor library - Ligand-based -
Acetyl CoA transferase inhibitor library - Ligand-based -
Acetylcholine nicotinic agonist library 269 Ligand-based -
Acetylcholine nicotinic antagonist library - Ligand-based -
Acute neurologic disorders treatment - Ligand-based -
ADP ribose polymerase inhibitor library - Ligand-based -
Adrenaline antagonist library - Ligand-based -
Adrenaline uptake inhibitor library - Ligand-based -
Aldose reductase inhibitor library - Ligand-based -
Anti-Helicobacter pylori library - Ligand-based -
Benzodiazepine agonist library - Ligand-based -
Benzodiazepine agonist partial library - Ligand-based -
Corticotropin releasing factor 1 receptor antagonist library - Ligand-based -
Cyclic GMP phosphodiesterase inhibitor library - Ligand-based -
Cyclooxygenase 1 inhibitor library 136 Ligand-based -
Dihydroorotate dehydrogenase inhibitor library - Ligand-based -
Dihydropteroate synthase inhibitor library - Ligand-based -
DNA topoisomerase inhibitor library - Ligand-based -
Endothelial growth factor antagonist library - Ligand-based -
Excitatory amino acid antagonist library - Ligand-based -
Factor VIIa inhibitor library - Ligand-based -
Gastrin inhibitor library - Ligand-based -
Growth hormone agonist library - Ligand-based -
Histamine release inhibitor library - Ligand-based -
Interleukin 1 antagonist library 49 Ligand-based -
Irritable Bowel syndrome treatment - Ligand-based -
Kallikrein inhibitor library - Ligand-based -
Lactamase C inhibitor library - Ligand-based -
Leukotriene B4 antagonist library - Ligand-based -
Leukotriene E4 antagonist library - Ligand-based -
Lipase inhibitor library - Ligand-based -
Lipid peroxidase inhibitor library - Ligand-based -
Lipoxygenase inhibitor library - Ligand-based -
Liver fibrosis treatment - Ligand-based -
Maillard reaction inhibitor library - Ligand-based -
NMDA receptor antagonist library 21 Ligand-based -
MAO B inhibitor library 182 Ligand-based -
Mediator release inhibitor library - Ligand-based -
Neurokinin 1 antagonist library - Ligand-based -
Neurokinin 3 antagonist library - Ligand-based -
Neuropeptide antagonist library - Ligand-based -
Neuropeptide Y antagonist library - Ligand-based -
Non-steroidal antiinflammatory agent library - Ligand-based -
Oxytocin antagonist library - Ligand-based -
Para amino benzoic acid antagonist library - Ligand-based -
Peroxisome proliferator-activated receptor agonist library - Ligand-based -
Peroxisome proliferator-activated receptor gamma agonist library 39 Ligand-based -
Phosphodiesterase inhibitor library - Ligand-based -
Phosphodiesterase V inhibitor library - Ligand-based -
Phospholipase A2 inhibitor library - Ligand-based -
Phospholipase inhibitor library - Ligand-based -
Platelet aggregation inhibitor library - Ligand-based -
Polarisation inhibitor library - Ligand-based -
Prostaglandin antagonist library - Ligand-based -
Prostaglandin synthase inhibitor library - Ligand-based -
Protease inhibitor library - Ligand-based -
Reverse transcriptase inhibitor library - Ligand-based -
Ribonucleoside diphosphate reductase inhibitor library - Ligand-based -
Ribonucleoside triphosphate reductase inhibitor library - Ligand-based -
Ribonucleotide reductase inhibitor library - Ligand-based -
S-adenosyl-L-methionine decarboxylase inhibitor library - Ligand-based -
Sigma receptor antagonist library - Ligand-based -
Stromelysin inhibitor library - Ligand-based -
Substance P antagonist library - Ligand-based -
Thromboxane A2 antagonist library - Ligand-based -
Thromboxane synthase inhibitor library - Ligand-based -
TNF convertase inhibitor library - Ligand-based -
Topoisomerase inhibitor library - Ligand-based -
Vanilloid antagonist library - Ligand-based -
VLA antagonist library - Ligand-based -
Xanthine oxidase inhibitor library - Ligand-based -

 

OTAVAchemicals Target-Focused Libraries collection
Name Number
Kinases 67
Proteases 12
GPCRs 25
Ion channels 5
Disease-based libraries 29
Epigenetic targets 7
Protein-Protein Interaction 2
Peptidomimetic 1
Nuclear Receptors 2
Glycomimetic 1
RNA binding 1
General Activities 128
Other 104

 

 

The libraries (SDF, XLS, PDF format) are available on request. Feel free to contact us or use on-line form below to send an inquiry if you are interested to obtain these libraries or if you need more information.

 

 

 

 

 

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