EGFR kinase

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EGFR kinase


7070707144

HDAC, EGFR, and HER2 Inhibitor

7-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-heptanoic acid hydroxyamide

Potent multi-acting HDAC, EGFR, and HER2 inhibitor.

HDAC enzyme assay IC50 = 6.5 nM, EGFR = 3.1 nM, HER2 = 19.0 nM

OTAVAchemicals Catalogue Number:  7070707144

CAS Registry Number:  1012054-55-5

Purity:  95%+

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0116690044

nw-egfr_inhibitor9

4-Amino-1-phenylpyrazolo[3,4-D]pyrimidine

 Potent inhibitor of EGF-R PTK with IC50 = 2.7 μM.

OTAVAchemicals Catalogue Number:   0116690044

CAS Registry Number:  5334-30-5

Purity: 98%

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0107930017

nw-egfr_inhibitor12

2-methoxy-4-[(E)-2-nitrovinyl]phenol

Potential antibacterial agent  against the Gram-positive bacteria (MIC = 256 mg/L)

OTAVAchemicals Catalogue Number:   0107930017

CAS Registry Number:  6178-42-3

Purity: 95%

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0108440152

nw-egfr_inhibitor11

N-benzylquinazolin-4-amine 

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 320 nM.

OTAVAchemicals Catalogue Number:   0108440152

CAS Registry Number:  N/A

Purity: 100%

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0108440170

nw-egfr_inhibitor10

N-phenylquinazolin-4-amine

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 344 nM.

OTAVAchemicals Catalogue Number:   0108440170

CAS Registry Number:  N/A

Purity: 99%

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0108440173

nw-egfr_inhibitor8

N-(m-tolyl)quinazolin-4-amine 

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 910 nM.

OTAVAchemicals Catalogue Number:   0108440173

CAS Registry Number:  N/A

Purity: 98%

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0108440177

nw-egfr_inhibitor7

N-(3-chlorophenyl)quinazolin-4-amine

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 23 nM.

OTAVAchemicals Catalogue Number:   0108440177

CAS Registry Number: N/A

Purity: 98%

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0108440188

nw-egfr_inhibitor6

N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine 

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 577 nM.

OTAVAchemicals Catalogue Number:   0108440188

CAS Registry Number:  N/A

Purity: 100%

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7011830583

nw-egfr_inhibitor5

N-(3-methoxyphenyl)quinazolin-4-amine

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 842 nM.

OTAVAchemicals Catalogue Number:   7011830583

CAS Registry Number:  N/A

Purity: 97%

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7015070078

nw-egfr_inhibitor4

6,7-dimethoxy-N-(4-methoxyphenyl)-quinazolin-4-amine 

Potent inhibitor of epidermal growth factor receptor erbB1 with IC50 = 0.25 μM.

Potent inhibitor of p56lck with IC50 = 10 μM.

OTAVAchemicals Catalogue Number:   7015070078

CAS Registry Number:  N/A

Purity: 99%

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7017500001

nw-egfr_inhibitor3

N-(3-fluorophenyl)-4-quinazolinamine hydrochloride

Potent inhibitor of EGF-R with IC50 = 56 nM.

OTAVAchemicals Catalogue Number:  7017500001

CAS Registry Number:  N/A

Purity: 100%

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7017500002

nw-egfr_inhibitor2

N-(3-bromophenyl)-4-quinazolinamine hydrochloride

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 27 nM.

OTAVAchemicals Catalogue Number:   7017500002

CAS Registry Number:  N/A

Purity: 98%

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7017500003

nw-egfr_inhibitor1

N-(3-iodophenyl)-4-quinazolinamine hydrochloride

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 80 nM.

OTAVAchemicals Catalogue Number:   7017500003

CAS Registry Number:  N/A

Purity: 98%

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7020540007

nw-inhibitor_of_egfr

N-[(4-methoxyphenyl)methyl]quinazolin-4-amine 

Potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 10 μM.

OTAVAchemicals Catalogue Number:   7020540007

CAS Registry Number:  N/A

Purity: 96%

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7020540711

EGFR-kinase_inhibitorN-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride

Inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase IC50 = 29 pM 

OTAVAchemicals Catalogue Number: 7020540711

CAS Registry Number: 153436-54-5

Purity: 95%+ (HPLC)

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